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Stent-based delivery of AAV2 vectors encoding oxidation-resistant apoA1

In-stent restenosis (ISR) complicates revascularization in the coronary and peripheral arteries. Apolipoprotein A1 (apoA1), the principal protein component of HDL possesses inherent anti-atherosclerotic and anti-restenotic properties. These beneficial traits are lost when wild type apoA1(WT) is subj...

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Detalles Bibliográficos
Autores principales: Hooshdaran, Bahman, Pressly, Benjamin B., Alferiev, Ivan S., Smith, Jonathan D., Zoltick, Philip W., Tschabrunn, Cory M., Wilensky, Robert L., Gorman, Robert C., Levy, Robert J., Fishbein, Ilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971450/
https://www.ncbi.nlm.nih.gov/pubmed/35361857
http://dx.doi.org/10.1038/s41598-022-09524-y