Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFv

Single chain antibody fragments (scFvs) are favored in diagnostic and therapeutic fields thanks to their small size and the availability of various engineering approaches. Linker between variable heavy (V(H)) and light (V(L)) chains of scFv covalently links these domains and it can affect scFv’s bio...

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Detalles Bibliográficos
Autores principales: Arslan, Merve, Karadag, Murat, Onal, Ebru, Gelinci, Emine, Cakan-Akdogan, Gulcin, Kalyoncu, Sibel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971466/
https://www.ncbi.nlm.nih.gov/pubmed/35361822
http://dx.doi.org/10.1038/s41598-022-09324-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971466/
https://www.ncbi.nlm.nih.gov/pubmed/35361822
http://dx.doi.org/10.1038/s41598-022-09324-4

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