Conformational plasticity of the HIV-1 gp41 immunodominant region is recognized by multiple non-neutralizing antibodies

The early humoral immune response to acute HIV-1 infection is largely non-neutralizing. The principal target of these antibodies is the primary immunodominant region (PID) on the gp41 fusion protein. The PID is a highly conserved 15-residue region displayed on the surface of HIV-1 virions. In this s...

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Detalles Bibliográficos
Autores principales: Cook, Jonathan D., Khondker, Adree, Lee, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971491/
https://www.ncbi.nlm.nih.gov/pubmed/35361878
http://dx.doi.org/10.1038/s42003-022-03235-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971491/
https://www.ncbi.nlm.nih.gov/pubmed/35361878
http://dx.doi.org/10.1038/s42003-022-03235-w

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