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Collateral responses to classical cytotoxic chemotherapies are heterogeneous and sensitivities are sparse

Chemotherapy resistance is a major obstacle to curing cancer patients. Combination drug regimens have shown promise as a method to overcome resistance; however, to date only some cancers have been cured with this method. Collateral sensitivity—the phenomenon whereby resistance to one drug is co-occu...

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Detalles Bibliográficos
Autores principales: Dalin, Simona, Grauman-Boss, Beatrice, Lauffenburger, Douglas A., Hemann, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971507/
https://www.ncbi.nlm.nih.gov/pubmed/35361803
http://dx.doi.org/10.1038/s41598-022-09319-1