A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Ion Channels

The identification of similar three-dimensional (3D) amino acid patterns among different proteins might be helpful to explain the polypharmacological profile of many currently used drugs. Also, it would be a reasonable first step for the design of novel multitarget compounds. Most of the current com...

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Detalles Bibliográficos
Autores principales: Valdés-Jiménez, Alejandro, Jiménez-González, Daniel, Kiper, Aytug K., Rinné, Susanne, Decher, Niels, González, Wendy, Reyes-Parada, Miguel, Núñez-Vivanco, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971525/
https://www.ncbi.nlm.nih.gov/pubmed/35370665
http://dx.doi.org/10.3389/fphar.2022.855792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971525/
https://www.ncbi.nlm.nih.gov/pubmed/35370665
http://dx.doi.org/10.3389/fphar.2022.855792

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