Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles

Engineered signaling networks can impart cells with new functionalities useful for directing differentiation and actuating cellular therapies. For such applications, the engineered networks must be tunable, precisely regulate target gene expression, and be robust to perturbations within the complex...

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Detalles Bibliográficos
Autores principales: Jones, Ross D., Qian, Yili, Ilia, Katherine, Wang, Benjamin, Laub, Michael T., Del Vecchio, Domitilla, Weiss, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971529/
https://www.ncbi.nlm.nih.gov/pubmed/35361767
http://dx.doi.org/10.1038/s41467-022-29338-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971529/
https://www.ncbi.nlm.nih.gov/pubmed/35361767
http://dx.doi.org/10.1038/s41467-022-29338-w

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