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Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits

Spatial disorientation is one of the earliest symptoms in Alzheimer’s disease and allocentric deficits can already be detected in the asymptomatic preclinical stages of the disease. The Morris Water Maze (MWM) is used to study spatial learning in rodent models. Here we investigated the spatial memor...

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Detalles Bibliográficos
Autores principales: Curdt, Nadine, Schmitt, Franziska W., Bouter, Caroline, Iseni, Trendelina, Weile, Hanna C., Altunok, Berfin, Beindorff, Nicola, Bayer, Thomas A., Cooke, Matthew B., Bouter, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971530/
https://www.ncbi.nlm.nih.gov/pubmed/35361814
http://dx.doi.org/10.1038/s41598-022-09270-1