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Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits
Spatial disorientation is one of the earliest symptoms in Alzheimer’s disease and allocentric deficits can already be detected in the asymptomatic preclinical stages of the disease. The Morris Water Maze (MWM) is used to study spatial learning in rodent models. Here we investigated the spatial memor...
Autores principales: | Curdt, Nadine, Schmitt, Franziska W., Bouter, Caroline, Iseni, Trendelina, Weile, Hanna C., Altunok, Berfin, Beindorff, Nicola, Bayer, Thomas A., Cooke, Matthew B., Bouter, Yvonne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971530/ https://www.ncbi.nlm.nih.gov/pubmed/35361814 http://dx.doi.org/10.1038/s41598-022-09270-1 |
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