Multi-omics analysis based on 3D-bioprinted models innovates therapeutic target discovery of osteosarcoma

Current in vitro models for osteosarcoma investigation and drug screening, including two-dimensional (2D) cell culture and tumour spheroids (i.e. cancer stem-like cells), lack extracellular matrix (ECM). Therefore, results from traditional models may not reflect real pathological processes in genuin...

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Detalles Bibliográficos
Autores principales: Lin, Yixuan, Yang, Yiqi, Yuan, Kai, Yang, Shengbing, Zhang, Shuhong, Li, Hanjun, Tang, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971536/
https://www.ncbi.nlm.nih.gov/pubmed/35415297
http://dx.doi.org/10.1016/j.bioactmat.2022.03.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971536/
https://www.ncbi.nlm.nih.gov/pubmed/35415297
http://dx.doi.org/10.1016/j.bioactmat.2022.03.029

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