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CHIP Decline Is Associated With Isoflurane-Induced Neurodegeneration in Aged Mice
Perioperative neurocognitive disorders (PND) commonly occur in elderly patients, and isoflurane could be a risk factor. During the pathogenesis of neurodegeneration, the ubiquitin–proteasome system (UPS) participates in the process of aging, which affects synaptic plasticity and synaptic function. H...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971621/ https://www.ncbi.nlm.nih.gov/pubmed/35368262 http://dx.doi.org/10.3389/fnins.2022.824871 |