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CHIP Decline Is Associated With Isoflurane-Induced Neurodegeneration in Aged Mice

Perioperative neurocognitive disorders (PND) commonly occur in elderly patients, and isoflurane could be a risk factor. During the pathogenesis of neurodegeneration, the ubiquitin–proteasome system (UPS) participates in the process of aging, which affects synaptic plasticity and synaptic function. H...

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Detalles Bibliográficos
Autores principales: Xu, Qiaoqiao, Xiong, Juan, Xu, Li, Wu, Yuanyuan, Li, Man, Li, Qinqin, Jiang, Tao, Luo, Ailin, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971621/
https://www.ncbi.nlm.nih.gov/pubmed/35368262
http://dx.doi.org/10.3389/fnins.2022.824871