Targeting Oncoproteins for Degradation by Small Molecule-Based Proteolysis-Targeting Chimeras (PROTACs) in Sex Hormone-Dependent Cancers

Sex hormone-dependent cancers, including breast, ovary, and prostate cancer, contribute to the high number of cancer-related deaths worldwide. Steroid hormones promote tumor occurrence, development, and metastasis by acting on receptors, such as estrogen receptors (ERs), androgen receptors (ARs), an...

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Detalles Bibliográficos
Autores principales: Liu, Li, Shi, Lihong, Wang, Zhaodi, Zeng, Jun, Wang, Yue, Xiao, Hongtao, Zhu, Yongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971670/
https://www.ncbi.nlm.nih.gov/pubmed/35370971
http://dx.doi.org/10.3389/fendo.2022.839857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971670/
https://www.ncbi.nlm.nih.gov/pubmed/35370971
http://dx.doi.org/10.3389/fendo.2022.839857

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