CX3CL1 Worsens Cardiorenal Dysfunction and Serves as a Therapeutic Target of Canagliflozin for Cardiorenal Syndrome

The prognosis of cardiorenal dysfunction induced by diabetes mellitus (DM), which belongs to cardiorenal syndrome type 5, is poor and its pathogenesis remains elusive. We have reported that CX3CL1 exacerbated heart failure and direct inhibition of CX3CL1 improved cardiac function. Emerging evidence...

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Detalles Bibliográficos
Autores principales: Zheng, Cankun, Xuan, Wanling, Chen, Zhenhuan, Zhang, Rui, Huang, Xiaoxia, Zhu, Yingqi, Ma, Siyuan, Chen, Kaitong, Chen, Lu, He, Mingyuan, Lin, Hairuo, Liao, Wangjun, Bin, Jianping, Liao, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971671/
https://www.ncbi.nlm.nih.gov/pubmed/35370759
http://dx.doi.org/10.3389/fphar.2022.848310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971671/
https://www.ncbi.nlm.nih.gov/pubmed/35370759
http://dx.doi.org/10.3389/fphar.2022.848310

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