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Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis

BACKGROUND: The combination of immune checkpoint blockade and chemotherapy has revolutionized the treatment of advanced gastric cancer (GC). It is crucial to unravel chemotherapy-induced tumor microenvironment (TME) modulation and identify which immunotherapy would improve antitumor effect. METHODS:...

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Detalles Bibliográficos
Autores principales: Xing, Xiaofang, Shi, Jinyao, Jia, Yongning, Dou, Yunsheng, Li, Zhongwu, Dong, Bin, Guo, Ting, Cheng, Xiaojing, Li, Xiaomei, Du, Hong, Hu, Ying, Jia, Shuqin, Zhang, Jian, Li, Ziyu, Ji, Jiafu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971786/
https://www.ncbi.nlm.nih.gov/pubmed/35361730
http://dx.doi.org/10.1136/jitc-2021-003984