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Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis
BACKGROUND: The combination of immune checkpoint blockade and chemotherapy has revolutionized the treatment of advanced gastric cancer (GC). It is crucial to unravel chemotherapy-induced tumor microenvironment (TME) modulation and identify which immunotherapy would improve antitumor effect. METHODS:...
Autores principales: | Xing, Xiaofang, Shi, Jinyao, Jia, Yongning, Dou, Yunsheng, Li, Zhongwu, Dong, Bin, Guo, Ting, Cheng, Xiaojing, Li, Xiaomei, Du, Hong, Hu, Ying, Jia, Shuqin, Zhang, Jian, Li, Ziyu, Ji, Jiafu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971786/ https://www.ncbi.nlm.nih.gov/pubmed/35361730 http://dx.doi.org/10.1136/jitc-2021-003984 |
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