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Targeting the Pseudomonas aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes

Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus. Here, we hypothesized that liposomes are capa...

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Detalles Bibliográficos
Autores principales: Wolfmeier, Heidi, Wardell, Samuel J. T., Liu, Leo T., Falsafi, Reza, Draeger, Annette, Babiychuk, Eduard B., Pletzer, Daniel, Hancock, Robert E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971843/
https://www.ncbi.nlm.nih.gov/pubmed/35369481
http://dx.doi.org/10.3389/fmicb.2022.867449