Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a(-/-) T Acute Lymphoblastic Leukemia

T lymphocyte acute lymphoblastic leukemia (T-ALL) is a heterogeneous disease affecting T cells at multiple stages of their development and is characterized by frequent genomic alterations. The transcription factor LEF1 is inactivated through mutation in a subset of T-ALL cases but elevated LEF1 expr...

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Detalles Bibliográficos
Autores principales: Carr, Tiffany, McGregor, Stephanie, Dias, Sheila, Verykokakis, Mihalis, Le Beau, Michelle M., Xue, Hai-Hui, Sigvardsson, Mikael, Bartom, Elizabeth T., Kee, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971981/
https://www.ncbi.nlm.nih.gov/pubmed/35371057
http://dx.doi.org/10.3389/fimmu.2022.845488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971981/
https://www.ncbi.nlm.nih.gov/pubmed/35371057
http://dx.doi.org/10.3389/fimmu.2022.845488

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