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Nonhuman Primate Adenoviruses of the Human Adenovirus B Species Are Potent and Broadly Acting Oncolytic Vector Candidates

The use of human adenoviruses (hAds) as oncolytic agents has demonstrated considerable potential. However, their efficacy in clinical studies is generally moderate and often varies between patients. This may, in part, be attributable to variable pre-existing neutralizing immunity in patients, which...

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Detalles Bibliográficos
Autores principales: Bots, Selas T.F., Kemp, Vera, Cramer, Steve J., van den Wollenberg, Diana J.M., Hornsveld, Marten, Lamfers, Martine L.M., van der Pluijm, Gabri, Hoeben, Rob C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972008/
https://www.ncbi.nlm.nih.gov/pubmed/34861769
http://dx.doi.org/10.1089/hum.2021.216