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Nonhuman Primate Adenoviruses of the Human Adenovirus B Species Are Potent and Broadly Acting Oncolytic Vector Candidates
The use of human adenoviruses (hAds) as oncolytic agents has demonstrated considerable potential. However, their efficacy in clinical studies is generally moderate and often varies between patients. This may, in part, be attributable to variable pre-existing neutralizing immunity in patients, which...
Autores principales: | Bots, Selas T.F., Kemp, Vera, Cramer, Steve J., van den Wollenberg, Diana J.M., Hornsveld, Marten, Lamfers, Martine L.M., van der Pluijm, Gabri, Hoeben, Rob C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972008/ https://www.ncbi.nlm.nih.gov/pubmed/34861769 http://dx.doi.org/10.1089/hum.2021.216 |
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