Glycerol-3-phosphate phosphatase operates a glycerol shunt in pancreatic β-cells that controls insulin secretion and metabolic stress

OBJECTIVE: The recently identified glycerol-3-phosphate (Gro3P) phosphatase (G3PP) in mammalian cells, encoded by the PGP gene, was shown to regulate glucose, lipid and energy metabolism by hydrolyzing Gro3P and to control glucose-stimulated insulin secretion (GSIS) in β-cells, in vitro. However, wh...

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Detalles Bibliográficos
Autores principales: Al-Mass, Anfal, Poursharifi, Pegah, Peyot, Marie-Line, Lussier, Roxane, Levens, Emily J., Guida, Julian, Mugabo, Yves, Possik, Elite, Ahmad, Rasheed, Al-Mulla, Fahd, Sladek, Robert, Madiraju, S.R.Murthy, Prentki, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972011/
https://www.ncbi.nlm.nih.gov/pubmed/35272070
http://dx.doi.org/10.1016/j.molmet.2022.101471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972011/
https://www.ncbi.nlm.nih.gov/pubmed/35272070
http://dx.doi.org/10.1016/j.molmet.2022.101471

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