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Glycerol-3-phosphate phosphatase operates a glycerol shunt in pancreatic β-cells that controls insulin secretion and metabolic stress
OBJECTIVE: The recently identified glycerol-3-phosphate (Gro3P) phosphatase (G3PP) in mammalian cells, encoded by the PGP gene, was shown to regulate glucose, lipid and energy metabolism by hydrolyzing Gro3P and to control glucose-stimulated insulin secretion (GSIS) in β-cells, in vitro. However, wh...
Autores principales: | Al-Mass, Anfal, Poursharifi, Pegah, Peyot, Marie-Line, Lussier, Roxane, Levens, Emily J., Guida, Julian, Mugabo, Yves, Possik, Elite, Ahmad, Rasheed, Al-Mulla, Fahd, Sladek, Robert, Madiraju, S.R.Murthy, Prentki, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972011/ https://www.ncbi.nlm.nih.gov/pubmed/35272070 http://dx.doi.org/10.1016/j.molmet.2022.101471 |
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