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Nanoscale‐tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo

Genetic modification to restore cell functions in the brain can be performed through the delivery of biomolecules in a minimally invasive manner into live neuronal cells within brain tissues. However, conventional nanoscale needles are too short (lengths of ~10 µm) to target neuronal cells in ~1‐mm‐...

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Detalles Bibliográficos
Autores principales: Numano, Rika, Goryu, Akihiro, Kubota, Yoshihiro, Sawahata, Hirohito, Yamagiwa, Shota, Matsuo, Minako, Iimura, Tadahiro, Tei, Hajime, Ishida, Makoto, Kawano, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972050/
https://www.ncbi.nlm.nih.gov/pubmed/35293154
http://dx.doi.org/10.1002/2211-5463.13377