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Nanoscale‐tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo
Genetic modification to restore cell functions in the brain can be performed through the delivery of biomolecules in a minimally invasive manner into live neuronal cells within brain tissues. However, conventional nanoscale needles are too short (lengths of ~10 µm) to target neuronal cells in ~1‐mm‐...
Autores principales: | Numano, Rika, Goryu, Akihiro, Kubota, Yoshihiro, Sawahata, Hirohito, Yamagiwa, Shota, Matsuo, Minako, Iimura, Tadahiro, Tei, Hajime, Ishida, Makoto, Kawano, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972050/ https://www.ncbi.nlm.nih.gov/pubmed/35293154 http://dx.doi.org/10.1002/2211-5463.13377 |
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