Cargando…

Feline XRCC4 undergoes rapid Ku‐dependent recruitment to DNA damage sites

Radiation and chemotherapy resistance remain some of the greatest challenges in human and veterinary cancer therapies. XRCC4, an essential molecule for nonhomologous end joining repair, is a promising target for radiosensitizers. Genetic variants and mutations of XRCC4 contribute to cancer susceptib...

Descripción completa

Detalles Bibliográficos
Autores principales: Koike, Manabu, Yutoku, Yasutomo, Koike, Aki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972062/
https://www.ncbi.nlm.nih.gov/pubmed/35000298
http://dx.doi.org/10.1002/2211-5463.13363