Rap1 Activity Is Essential for Focal Adhesion and Slit Diaphragm Integrity

Glomerular podocytes build, with their intercellular junctions, part of the kidney filter. The podocyte cell adhesion protein, nephrin, is essential for developing and maintaining slit diaphragms as functional loss in humans results in heavy proteinuria. Nephrin expression and function are also alte...

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Detalles Bibliográficos
Autores principales: Maywald, Mee-Ling, Picciotto, Cara, Lepa, Carolin, Bertgen, Luisa, Yousaf, Farwah Sanam, Ricker, Andrea, Klingauf, Jürgen, Krahn, Michael P., Pavenstädt, Hermann, George, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972170/
https://www.ncbi.nlm.nih.gov/pubmed/35372328
http://dx.doi.org/10.3389/fcell.2022.790365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972170/
https://www.ncbi.nlm.nih.gov/pubmed/35372328
http://dx.doi.org/10.3389/fcell.2022.790365

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