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Three interacting regions of the Ndc80 and Dam1 complexes support microtubule tip-coupling under load

Accurate mitosis requires kinetochores to make persistent, load-bearing attachments to dynamic microtubule tips, thereby coupling chromosome movements to tip growth and shortening. This tip-coupling behavior depends on the conserved Ndc80 complex and, in budding yeast, on the Dam1 complex, which bin...

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Detalles Bibliográficos
Autores principales: Flores, Rachel L., Peterson, Zachary E., Zelter, Alex, Riffle, Michael, Asbury, Charles L., Davis, Trisha N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972186/
https://www.ncbi.nlm.nih.gov/pubmed/35353161
http://dx.doi.org/10.1083/jcb.202107016