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A Set of Experimentally Validated Decoys for the Human CC Chemokine Receptor 7 (CCR7) Obtained by Virtual Screening

We present a state-of-the-art virtual screening workflow aiming at the identification of novel CC chemokine receptor 7 (CCR7) antagonists. Although CCR7 is associated with a variety of human diseases, such as immunological disorders, inflammatory diseases, and cancer, this target is underexplored in...

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Detalles Bibliográficos
Autores principales: Proj, Matic, De Jonghe, Steven, Van Loy, Tom, Jukič, Marko, Meden, Anže, Ciber, Luka, Podlipnik, Črtomir, Grošelj, Uroš, Konc, Janez, Schols, Dominique, Gobec, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972196/
https://www.ncbi.nlm.nih.gov/pubmed/35370691
http://dx.doi.org/10.3389/fphar.2022.855653