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Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis-fibroblast-like synoviocytes by inhibiting the NF-κB and MAPK signaling pathways

Rheumatoid arthritis (RA) is a chronic inflammatory disease that mainly targets the synovial membrane, thus causing stiffness, deformity and dysfunction of joints. To date, no effective anti-inflammatory treatments are available for RA. Piceatannol (PIC) is a natural derivative of resveratrol, which...

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Detalles Bibliográficos
Autores principales: Gao, Xuezhong, Kang, Xiaodiao, Lu, Hongwei, Xue, Enxing, Chen, Rong, Pan, Jun, Ma, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972314/
https://www.ncbi.nlm.nih.gov/pubmed/35322865
http://dx.doi.org/10.3892/mmr.2022.12696