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Global fitting of multiple data frames from SEC–SAXS to investigate the structure of next-generation nanodiscs

The combination of online size-exclusion chromatography and small-angle X-ray scattering (SEC–SAXS) is rapidly becoming a key technique for structural investigations of elaborate biophysical samples in solution. Here, a novel model-refinement strategy centred around the technique is outlined and its...

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Detalles Bibliográficos
Autores principales: Barclay, Abigail, Tidemand Johansen, Nicolai, Tidemand, Frederik Grønbæk, Arleth, Lise, Pedersen, Martin Cramer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972807/
https://www.ncbi.nlm.nih.gov/pubmed/35362471
http://dx.doi.org/10.1107/S2059798322001838