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Intratarget Microdosing for Deep Phenotyping of Multiple Drug Effects in the Live Brain

A main impediment to effective development of new therapeutics for central nervous system disorders, and for the in vivo testing of biological hypotheses in the brain, is the ability to rapidly measure the effect of novel agents and treatment combinations on the pathophysiology of native brain tissu...

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Detalles Bibliográficos
Autores principales: Kim, Jennifer, Ahn, Sebastian W., Deans, Kyle, Thompson, Devon, Ferland, Benjamin, Divakar, Prajan, Dominas, Christine, Jonas, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973214/
https://www.ncbi.nlm.nih.gov/pubmed/35372313
http://dx.doi.org/10.3389/fbioe.2022.855755