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Spatial Distribution of Intracellular Ion Concentrations in Aggregate‐Forming HeLa Cells Analyzed by μ‐XRF Imaging

Protein aggregation is a hallmark of several severe neurodegenerative disorders such as Huntington's, Parkinson's, or Alzheimer's disease. Metal ions play a profound role in protein aggregation and altered metal‐ion homeostasis is associated with disease progression. Here we utilize μ...

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Detalles Bibliográficos
Autores principales: Gräfenstein, Andreas, Rumancev, Christoph, Pollak, Roland, Hämisch, Benjamin, Galbierz, Vanessa, Schroeder, Walter H., Garrevoet, Jan, Falkenberg, Gerald, Vöpel, Tobias, Huber, Klaus, Ebbinghaus, Simon, Rosenhahn, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973254/
https://www.ncbi.nlm.nih.gov/pubmed/35363437
http://dx.doi.org/10.1002/open.202200024