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First-in-Humans Evaluation of a PD-L1–Binding Peptide PET Radiotracer in Non–Small Cell Lung Cancer Patients

(68)Ga-NOTA-WL12 is a peptide-based PET imaging agent. We conducted a first-in-human study of (68)Ga-NOTA-WL12 for PET to study the in vivo biodistribution, metabolism, radiation dosimetry, safety, and potential for quantifying programmed death ligand-1 (PD-L1) expression levels in patients with adv...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Jiang, Jinquan, Yang, Xue, Liu, Teli, Ding, Jin, Nimmagadda, Sridhar, Pomper, Martin G., Zhu, Hua, Zhao, Jun, Yang, Zhi, Li, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973283/
https://www.ncbi.nlm.nih.gov/pubmed/34326125
http://dx.doi.org/10.2967/jnumed.121.262045