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Phase I Trial of (99m)Tc-(HE)(3)-G3, a DARPin-Based Probe for Imaging of HER2 Expression in Breast Cancer

Radionuclide molecular imaging of human epidermal growth factor receptor type 2 (HER2) expression may enable a noninvasive discrimination between HER2-positive and HER2-negative breast cancers for stratification of patients for HER2-targeted treatments. DARPin (designed ankyrin repeat proteins) G3 i...

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Detalles Bibliográficos
Autores principales: Bragina, Olga, Chernov, Vladimir, Schulga, Alexey, Konovalova, Elena, Garbukov, Eugeniy, Vorobyeva, Anzhelika, Orlova, Anna, Tashireva, Liubov, Sörensen, Jens, Zelchan, Roman, Medvedeva, Anna, Deyev, Sergey, Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973295/
https://www.ncbi.nlm.nih.gov/pubmed/34385343
http://dx.doi.org/10.2967/jnumed.121.262542