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Membrane potential‐dependent regulation of mitochondrial complex II by oxaloacetate in interscapular brown adipose tissue

Classically, mitochondrial respiration responds to decreased membrane potential (ΔΨ) by increasing respiration. However, we found that for succinate‐energized complex II respiration in skeletal muscle mitochondria (unencumbered by rotenone), low ΔΨ impairs respiration by a mechanism culminating in o...

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Detalles Bibliográficos
Autores principales: Fink, Brian D., Rauckhorst, Adam J., Taylor, Eric B., Yu, Liping, Sivitz, William I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973305/
https://www.ncbi.nlm.nih.gov/pubmed/35392250
http://dx.doi.org/10.1096/fba.2021-00137