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Susceptibility to thiopurine toxicity by TPMT and NUDT15 variants in Colombian children with acute lymphoblastic leukemia

OBJECTIVE: This study aimed to correlate the genetic profile of the NUDT15 and TPMT genes with the side effects of the treatment of pediatric patients with acute lymphoid leukemia who were undergoing maintenance therapy at a tertiary care hospital in 2017. METHODS: This was an analytical, longitudin...

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Detalles Bibliográficos
Autores principales: Correa-Jimenez, Oscar, Yunis, Juan José, Linares-Ballesteros, Adriana, Sarmiento-Urbina, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Universidad del Valle 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973308/
https://www.ncbi.nlm.nih.gov/pubmed/35431360
http://dx.doi.org/10.25100/cm.v52i3.4569