5-(Sulfamoyl)thien-2-yl 1,3-oxazole inhibitors of carbonic anhydrase II with hydrophilic periphery

Hydrophilic derivatives of an earlier described series of carbonic anhydrase inhibitors have been designed, prepared and profiled against a panel of carbonic anhydrase isoforms, including the glaucoma-related hCA II. For all hydrophilic derivatives, computational prediction of intraocular permeabili...

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Detalles Bibliográficos
Autores principales: Kalinin, Stanislav, Kovalenko, Alexander, Valtari, Annika, Nocentini, Alessio, Gureev, Maxim, Urtti, Arto, Korsakov, Mikhail, Supuran, Claudiu T., Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973362/
https://www.ncbi.nlm.nih.gov/pubmed/35350949
http://dx.doi.org/10.1080/14756366.2022.2056733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973362/
https://www.ncbi.nlm.nih.gov/pubmed/35350949
http://dx.doi.org/10.1080/14756366.2022.2056733

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