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Advances in siRNA therapeutics and synergistic effect on siRNA activity using emerging dual ribose modifications

Nucleic acid-based therapeutics that control gene expression have been steadily progressing towards achieving their full clinical potential throughout the last few decades. Rapid progress has been achieved in RNAi-based therapy by optimizing high specificity and gene silencing efficiency using chemi...

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Detalles Bibliográficos
Autores principales: Gangopadhyay, Sumit, Gore, Kiran R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973385/
https://www.ncbi.nlm.nih.gov/pubmed/35352626
http://dx.doi.org/10.1080/15476286.2022.2052641