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Mitochondrial Reactive Oxygen Species Mediate Activation of TRPV1 and Calcium Entry Following Peripheral Sensory Axotomy

Axons that are physically separated from their soma activate a series of signaling events that results in axonal self-destruction. A critical element of this signaling pathway is an intra-axonal calcium rise that occurs just prior to axonal fragmentation. Previous studies have shown that preventing...

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Detalles Bibliográficos
Autores principales: Kievit, Bradley, Johnstone, Aaron D., Gibon, Julien, Barker, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973397/
https://www.ncbi.nlm.nih.gov/pubmed/35370552
http://dx.doi.org/10.3389/fnmol.2022.852181