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Investigating effect of mutation on structure and function of G6PD enzyme: a comparative molecular dynamics simulation study

Several natural mutants of the human G6PD enzyme exist and have been reported. Because the enzymatic activities of many mutants are different from that of the wildtype, the genetic polymorphism of G6PD plays an important role in the synthesis of nucleic acids via ribulose-5-phosphate and formation o...

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Detalles Bibliográficos
Autores principales: Rani, Sadaf, Malik, Fouzia Perveen, Anwar, Jamshed, Zafar Paracha, Rehan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973466/
https://www.ncbi.nlm.nih.gov/pubmed/35368337
http://dx.doi.org/10.7717/peerj.12984