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Aberrant Cholesterol Metabolic Genes Regulation in a Negative Feedback Loop Induced by an Alphacoronavirus

Porcine epidemic diarrhea virus (PEDV) is an alphacoronavirus that causes acute inflammation and severe diarrhea in newborn piglets with a high mortality rate. Given that cholesterol is required for coronavirus infection in vitro, the role of endogenous cholesterol metabolism in regulating coronavir...

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Detalles Bibliográficos
Autores principales: Liu, Hao-Yu, Gu, Haotian, Qu, Huan, Bao, Wenbin, Li, Yanhua, Cai, Demin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973467/
https://www.ncbi.nlm.nih.gov/pubmed/35369058
http://dx.doi.org/10.3389/fnut.2022.870680