Columbianetin alleviates lipopolysaccharides (LPS)-induced inflammation and apoptosis in chondrocyte through activation of autophagy by inhibiting serum and glucocorticoid-induced protein kinase 1 (SGK1) expression

Osteoarthritis (OA) is a degenerative disease of articular cartilage involving the entire joint tissue. Columbianetin (CBT) is a major active compound of radix angelicae pubescentis, which is used in the treatment of OA. This paper attempts to explore the role of CBT in OA. Lipopolysaccharides (LPS)...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Zheng, Haotian, Zhang, Xuan, Xu, Yude, Fu, Zhibin, Ji, Xing, Wei, Changhao, An, Guoyao, Tan, Mingyuan, Zhou, Mingwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973585/
https://www.ncbi.nlm.nih.gov/pubmed/35129051
http://dx.doi.org/10.1080/21655979.2022.2032970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973585/
https://www.ncbi.nlm.nih.gov/pubmed/35129051
http://dx.doi.org/10.1080/21655979.2022.2032970

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