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Paeoniflorin alleviates NG-nitro-L-arginine methyl ester (L-NAME)-induced gestational hypertension and upregulates silent information regulator 2 related enzyme 1 (SIRT1) to reduce H(2)O(2)-induced endothelial cell damage

Pregnancy-induced hypertension (PIH) is a leading cause of maternal mortality. Paeoniflorin has been reported to alleviate hypertension, thus relieving the injury of target organ. This study aimed to investigate the role of paeoniflorin in PIH development by regulating SIRT1 in rats. The mean arteri...

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Detalles Bibliográficos
Autores principales: Wu, Jingjing, Zhang, Dongmei, Hu, Linlin, Zheng, Xiaowei, Chen, Caihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973614/
https://www.ncbi.nlm.nih.gov/pubmed/35030965
http://dx.doi.org/10.1080/21655979.2021.2024325