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Paeoniflorin alleviates NG-nitro-L-arginine methyl ester (L-NAME)-induced gestational hypertension and upregulates silent information regulator 2 related enzyme 1 (SIRT1) to reduce H(2)O(2)-induced endothelial cell damage
Pregnancy-induced hypertension (PIH) is a leading cause of maternal mortality. Paeoniflorin has been reported to alleviate hypertension, thus relieving the injury of target organ. This study aimed to investigate the role of paeoniflorin in PIH development by regulating SIRT1 in rats. The mean arteri...
Autores principales: | Wu, Jingjing, Zhang, Dongmei, Hu, Linlin, Zheng, Xiaowei, Chen, Caihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973614/ https://www.ncbi.nlm.nih.gov/pubmed/35030965 http://dx.doi.org/10.1080/21655979.2021.2024325 |
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