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Overexpression of microRNA-381-3p ameliorates hypoxia/ischemia-induced neuronal damage and microglial inflammation via regulating the C-C chemokine receptor type 2 /nuclear transcription factor-kappa B axis

microRNAs, as small endogenous RNAs, influence umpteen sophisticated cellular biological functions regarding neurodegenerative and cerebrovascular diseases. Here, we interrogated miR-381-3p’s influence on BV2 activation and neurotoxicity in ischemic and hypoxic environment. Oxygen-glucose deprivatio...

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Detalles Bibliográficos
Autores principales: Che, Yuanmei, He, Jianglong, Li, Xiaopeng, Wu, Daxian, Zhang, Yi, Yuan, Guicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973660/
https://www.ncbi.nlm.nih.gov/pubmed/35246016
http://dx.doi.org/10.1080/21655979.2022.2038448