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LncRNA LINC00525 activates HIF-1α through miR-338-3p / UBE2Q1 / β-catenin axis to regulate the Warburg effect in colorectal cancer

Warburg effect is considered to be related to the malignancy of tumor cells under hypoxic conditions, but the underlying mechanism remains unknown. In this article, it has been reported that lncRNA LINC00525 is a hypoxia-responsive lncRNA and is essential for hypoxia-enhanced glycolysis. It was foun...

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Detalles Bibliográficos
Autores principales: Meng, Fanqi, Luo, Xiaofan, Li, Chenyao, Wang, Guangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973709/
https://www.ncbi.nlm.nih.gov/pubmed/35156520
http://dx.doi.org/10.1080/21655979.2021.2018538