Synergistic anticancer effects of everolimus (RAD001) and Rhein on gastric cancer cells via phosphoinositide-3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway

Everolimus (RAD001) is a mTOR inhibitor and is widely used for the treatment of gastric cancer (GC). Evidence suggests that Rhein has anticancer effect on GC. But the synergistic effect and mechanism of RAD001 and Rhein combination on GC is not clear. The current study aims to clarify the combinatio...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Li, Rui, Wei, Pei-Feng, Ou, Li, Li, Min, Bai, Yang, Luo, Wen-Jia, Fan, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973710/
https://www.ncbi.nlm.nih.gov/pubmed/35209807
http://dx.doi.org/10.1080/21655979.2021.2005988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973710/
https://www.ncbi.nlm.nih.gov/pubmed/35209807
http://dx.doi.org/10.1080/21655979.2021.2005988

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