SREBP2 promotes the viability, proliferation, and migration and inhibits apoptosis in TGF-β1-induced airway smooth muscle cells by regulating TLR2/NF-κB/NFATc1/ABCA1 regulatory network

Asthma is a respiratory disease with complex pathogenesis. Sterol-responsive element-binding proteins 2 (SREBP2) was found to bind to promoter sequences of ABCA1 to suppress ABCA1 promoter activity. This study aimed to explore the expression level of SREBP2 and ATP-binding cassette transporter A1 (A...

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Detalles Bibliográficos
Autores principales: Wang, Yuebin, Yang, Huike, Su, Xian, Cao, Anqiang, Chen, Feng, Chen, Peng, Yan, Fangtao, Hu, Huirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973716/
https://www.ncbi.nlm.nih.gov/pubmed/35037821
http://dx.doi.org/10.1080/21655979.2022.2026550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973716/
https://www.ncbi.nlm.nih.gov/pubmed/35037821
http://dx.doi.org/10.1080/21655979.2022.2026550

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