Cargando…
SREBP2 promotes the viability, proliferation, and migration and inhibits apoptosis in TGF-β1-induced airway smooth muscle cells by regulating TLR2/NF-κB/NFATc1/ABCA1 regulatory network
Asthma is a respiratory disease with complex pathogenesis. Sterol-responsive element-binding proteins 2 (SREBP2) was found to bind to promoter sequences of ABCA1 to suppress ABCA1 promoter activity. This study aimed to explore the expression level of SREBP2 and ATP-binding cassette transporter A1 (A...
Autores principales: | Wang, Yuebin, Yang, Huike, Su, Xian, Cao, Anqiang, Chen, Feng, Chen, Peng, Yan, Fangtao, Hu, Huirong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973716/ https://www.ncbi.nlm.nih.gov/pubmed/35037821 http://dx.doi.org/10.1080/21655979.2022.2026550 |
Ejemplares similares
-
TGF-β1/SMOC2/AKT and ERK axis regulates proliferation, migration, and fibroblast to myofibroblast transformation in lung fibroblast, contributing with the asthma progression
por: Wang, Yuebin, et al.
Publicado: (2021) -
Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1–SREBP pathway
por: Zhang, Yanhong, et al.
Publicado: (2022) -
NFATC1 and NFATC2 expression patterns in human osteochondromas
por: Wang, Yuanyuan, et al.
Publicado: (2023) -
Regulation of microRNA-33, SREBP and ABCA1 genes in a mouse model of high cholesterol
por: Zhang, Xianglun, et al.
Publicado: (2021) -
IRAK1 mediates TLR4-induced ABCA1 downregulation and lipid accumulation in VSMCs
por: Guo, L, et al.
Publicado: (2015)