Berberine represses Wnt/β-catenin pathway activation via modulating the microRNA-103a-3p/Bromodomain-containing protein 4 axis, thereby refraining pyroptosis and reducing the intestinal mucosal barrier defect induced via colitis

Intestinal barrier dysfunction is inflammatory bowel disease’s hallmark. Berberine (BBR) has manifested its anti-inflammatory properties in colitis. For exploring the molecular mechanism of BBR’s impacts on colitis, application of a dextran sodium sulfate-induced mouse colitis in vivo model was with...

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Detalles Bibliográficos
Autores principales: Zhao, Xun, Cui, DeJun, Yuan, WenQiang, Chen, Chen, Liu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973728/
https://www.ncbi.nlm.nih.gov/pubmed/35259053
http://dx.doi.org/10.1080/21655979.2022.2047405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973728/
https://www.ncbi.nlm.nih.gov/pubmed/35259053
http://dx.doi.org/10.1080/21655979.2022.2047405

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