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Isoform-specific functions of PPARγ in gene regulation and metabolism

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that is a vital regulator of adipogenesis, insulin sensitivity, and lipid metabolism. Activation of PPARγ by antidiabetic thiazolidinediones (TZD) reverses insulin resistance but also leads to weight gain that limits the use...

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Detalles Bibliográficos
Autores principales: Hu, Wenxiang, Jiang, Chunjie, Kim, Mindy, Xiao, Yang, Richter, Hannah J., Guan, Dongyin, Zhu, Kun, Krusen, Brianna M., Roberts, Arielle N., Miller, Jessica, Steger, David J., Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973844/
https://www.ncbi.nlm.nih.gov/pubmed/35273075
http://dx.doi.org/10.1101/gad.349232.121