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Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states

In mammals, the conserved telomere binding protein Rap1 serves a diverse set of nontelomeric functions, including activation of the NF-kB signaling pathway, maintenance of metabolic function in vivo, and transcriptional regulation. Here, we uncover the mechanism by which Rap1 modulates gene expressi...

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Detalles Bibliográficos
Autores principales: Barry, Raymond Mario, Sacco, Olivia, Mameri, Amel, Stojaspal, Martin, Kartsonis, William, Shah, Pooja, De Ioannes, Pablo, Hofr, Ctirad, Côté, Jacques, Sfeir, Agnel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973845/
https://www.ncbi.nlm.nih.gov/pubmed/35210222
http://dx.doi.org/10.1101/gad.349039.121